High School

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Place in the correct order the events that occur when a bacterial pathogen causes disease. Start at the top.

1. The pathogen enters the host organism.
2. The pathogen adheres to host cells.
3. The pathogen invades host tissues.
4. The pathogen evades the host's immune response.
5. The pathogen damages host tissues or produces toxins.

Answer :

The correct order of events when a bacterial pathogen causes disease starts with exposure, followed by adhesion, invasion, infection, and ends with transmission.

When a bacterial pathogen causes disease, it must go through a series of stages in a specific sequence. These stages are exposure, adhesion (colonization), invasion, infection, and transmission. Let's outline these stages in detail:

  1. Exposure: The initial contact between the pathogen and the host. Pathogens enter through portals of entry such as the respiratory tract, skin, or mucous membranes. This stage is where the bacterial pathogen first makes contact with the host.
  2. Adhesion: This is colonization where the pathogen adheres to the host's cells using specific molecules called adhesins. A pathogen must attach to host cells to establish a site for infection.
  3. Invasion: Following adhesion, the pathogen invades body tissue. During this stage, pathogens may produce enzymes that help them penetrate host tissues.
  4. Infection: Once the pathogen has invaded, it multiplies and starts to cause disease, either through direct damage to host cells or by producing toxins.
  5. Transmission: The final stage involves the pathogen exiting the host and moving on to infect another host, thereby continuing the cycle of disease.

The success of a pathogen in causing disease depends on its ability to complete each of these stages effectively while overcoming or evading the host's immune response.

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Rewritten by : Jeany