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During translation, what is the correct order of events that occur as an amino acid is added to a growing polypeptide chain?

A. Translocation, codon recognition, termination
B. Peptide bond formation, translocation, codon recognition
C. Initiation, codon recognition, termination
D. Codon recognition, peptide bond formation, translocation

Answer :

Final answer:

The correct order of events during translation as an amino acid is added to a growing polypeptide chain is: codon recognition, peptide bond formation, translocation, and termination.

Explanation:

The correct order of events during translation as an amino acid is added to a growing polypeptide chain is:

  1. Codon recognition: Transitional complex forms, and a tRNA brings the first amino acid in the polypeptide chain to bind to the start codon on mRNA.
  2. Peptide bond formation: A peptide bond is catalyzed between the amino group of the amino acid on the second tRNA and the carboxyl group of the amino acid on the first tRNA. Peptidyl transferase catalyzes this reaction.
  3. Translocation: The ribosome moves one codon along the mRNA, shifting the tRNA from the A site to the P site and the tRNA from the P site to the E site. This movement requires energy derived from GTP hydrolysis.
  4. Termination: Termination occurs when the ribosome encounters a stop codon. Release factors cause the polypeptide to be released, and the ribosomal complex dissociates.

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