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Answer :
In the context of vaccine production, antigens from microbial pathogens play a crucial role because they stimulate the immune system to recognize and combat the pathogens if the person is exposed in the future. Let's discuss the characteristics of antigens that are typically considered when developing vaccines:
Must be secreted or found on the surface of the pathogen: This is a necessary characteristic because surface or secreted antigens are accessible to the immune system. The immune system, particularly antibodies, can recognize these antigens more effectively, helping to prevent or control infection.
Must be found in all strains of the pathogen: This characteristic, while beneficial, is not strictly required. It is preferable for a vaccine to target antigens found in all strains of a pathogen to ensure broad protection. However, vaccines can still be effective even if this is not the case, possibly requiring updates or boosters for different strains, as observed with the influenza vaccine.
Based on the options provided, the characteristic that is not required for antigens used in vaccine production is:
- Must be found in all strains of the pathogen.
Vaccine efficacy can vary between different strains, and some vaccines are strain-specific, making this characteristic less of an absolute requirement.
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